Based on a shounen manga by Ookubo Atsushi serialised in Shounen Gangan.
Set in the Shinigami technical school for weapon technicians, the series revolves around three pairs of two characters with each having a weapon technician and a human weapon. They try to make the latter a "Death Scythe" and thus fit for use by the Shinigami. They must collect the souls of 99 evil humans and one witch to do this.
Note: There are two versions of Soul Eater. The first is a normal version which airs on Mondays and the second is a "Late Show" version which airs on Thursday nights. The "Late Show" version has some extra scenes added during eye-catches and before the next episode preview but the main part of the show doesn't have any differences from the normal version.